Ig Igiteranyo IgE Chemiluminescense Immunoassay Kit

Hano haribintu bitanu birinda immunoglobulin, G, M, A, D, E, IgE nibirimo bike, ariko kandi ubwoko bwa hypersensitivite bwihuse bufitanye isano.IgE mubisanzwe yicara hejuru ya selile ya mast na basofile, allergens yinjira hanze, hanyuma IgE ihita itegeka izo selile zombi binyuze muri reseptor ya fc.Ingirabuzimafatizo za mast na basofile zimaze kwangirika, zirekura ibintu byinshi bidasanzwe nka histamine, kinins, leukotriène, na prostaglandine D2.Izi ngingo zizaganisha ku ruhererekane rw’imyumvire ikabije y’indwara, ibuza ibikorwa bya IgE, bizagabanya neza urugero rwa hyperensitivite.

IgE ni ubwoko bwa immunoglobuline yavumbuwe mu 1966 ifite uburemere bwa 188kD.Ibiri muri IgE muri serumu ni bike cyane, bingana na 0.002% gusa ya Ig yose muri serumu.Ihinduranya bitinze kuri ontogeny.IgE ikorwa cyane cyane na plasma selile muri lamina propria ya mucosa, nka nasofarynx, toniilles, bronchi, na gastrointestinal tract.Ibi bice akenshi ni ahantu haterwa allerge nubwoko bwa allergie.IgE ni antibody ya cytophilique, uturere dukora twa Cε2 na Cε3 turashobora guhuza cyane-FcεRI-hafi cyane ya membrane ya basofile na selile mast.Iyo allergen yongeye kwinjira mu mubiri, ihuza IgE yashyizwe kuri basofili na selile ya mast, ishobora gutera ubwoko bwa I allergique.Kumenya IgE yose irashobora gukoreshwa mugufasha mugupima asima ya allergique, rhinite yigihe cya allergique, dermatite atopic, pneumoniya iterwa nibiyobyabwenge, bronchopulmonary aspergillose, ibibembe, pemphigoide nindwara zimwe na zimwe za parasitike.

Uburyo bukoreshwa muburyo bwo kumenya IgE yose mumavuriro harimo fluorescence immunoassay, immunoassay ifitanye isano na enzyme (ELISA), immunoassay ya chemiluminescence (CLIA).Kubijyanye no kwiyemeza kwuzuye kwa Ige, irinde kurya urusenda, ibiryo byo mu nyanja nibindi biribwa bikunze kwibasirwa na allergie, kugirango utongera ibimenyetso bya allergie.