Imikorere yimpyiko Chemiluminescense Immunoassay Kit

Impyiko nimwe mu ngingo zingenzi zumubiri wumuntu, imikorere yazo ahanini isohoka kandi isohoka inkari, imyanda, uburozi nibiyobyabwenge;Kugenzura no kubungabunga ingano yumubiri hamwe nibigize (amazi numuvuduko wa osmotic, electrolytite, pH);Komeza kuringaniza ibidukikije byimbere mu mubiri (umuvuduko wamaraso, endocrine).Ibizamini byimikorere yimpyiko harimo urea, creatinine, aside uric, β 2-microglobuline, cystatine C, microalbumin yinkari, proteine ​​yuzuye, neutrophil gelatinase ifitanye isano na lipide itwara lipide, α 1-microglobuline, retinol ihuza protein, n-acetyl-glucosidase, nibindi.

Urea nigicuruzwa cyanyuma cya poroteyine na aside amine metabolism kandi gisohoka cyane nimpyiko.Ubusanzwe Urea iboneka mugupima ingano ya azote ya urea, ifite akamaro kanini mugupima, kuvura no guhanura imikorere mibi yimpyiko.

Creatinine ni uburemere buke bwa metabolite yumuntu isanzwe inyura muyungurura isi yose itiriwe isubizwa na tubules yimpyiko.Kubwibyo, kwibanda kumaraso hamwe ninkari creinine ni ikimenyetso cyerekana imikorere ya filteri yisi yose, ishobora gukoreshwa mugupima ubwoko butandukanye bwindwara zimpyiko zidakira no gukurikirana imiti ivura imiti, ndetse no gukurikirana dialyse yimpyiko.

Acide Uric nigicuruzwa cyanyuma cya purine metabolism.Kwipimisha aside Uric ikoreshwa muburwayi butandukanye bwa neprotique na metabolike, harimo kunanirwa kw'impyiko, gout, leukemia, psoriasis, inzara, cyangwa izindi ndwara zangiza, ndetse no gukurikirana gusuzuma no kuvura abarwayi bahabwa imiti ya cytotoxique.Acide Uric ifatwa nkikimenyetso cyo gusuzuma indwara ya goutte iterwa na purine metabolism disorder.

Ubwiyongere bwa β 2-microglobuline muri serumu burashobora kwerekana niba imikorere ya filteri yisi yose yangiritse cyangwa umutwaro wo kuyungurura wiyongereye, mugihe kwiyongera kwa β 2-microglobuline mu nkari bishobora kwerekana ibyangiritse cyangwa umutwaro wo kuyungurura wiyongereye.Muri pyelonephritis ikaze kandi idakira, inkari β 2-microglobuline yiyongera kubera kwangirika kw'impyiko, naho muri cystite, β 2-microglobuline ni ibisanzwe.

Cystatin C ibaho cyane mu ngirabuzimafatizo no mu mazi yo mu mubiri.Nuburemere buke bwa molekuline, poroteyine ya alkaline unglycosylated ifite uburemere bwa 13.3KD, igizwe n’ibisigisigi bya aside amine 122, kandi birashobora gukorwa ningirabuzimafatizo zose ziri mu mubiri ku gipimo gihoraho.Nubwoko bwa endogenous marike kugirango bugaragaze impinduka zifatika mugipimo cyo kuyungurura isi, no muburyo bwa tubule reubake ya tubule, ariko byabaye nyuma yo kwangirika gukabije kwa metabolism kubora, ntibisubize amaraso, kubwibyo, ubwinshi bwamaraso bwayo bugenwa nigipimo cyo kuyungurura isi. , kandi ntibiterwa nibintu byose byo hanze, nk'uburinganire, imyaka, imirire, ni ubwoko bwiza bwa endogenous marike kugirango bugaragaze impinduka zifatika mugipimo cyo kuyungurura isi.

Kugena microalbumin mu nkari byerekana nepropatique hakiri kare no gukomeretsa kw'impyiko increase kwiyongera kw'indwara ya diabete ya nepropatique, hypertension, gutwita kwa preeclampsia.Mugihe cyambere cya microalbumin yinkari ni ikimenyetso cyambere nibimenyetso byo kubaho kwa nepropatique.Muri iki gihe, kwangirika kwimpyiko biracyari mubihe bidasubirwaho.Niba ubuvuzi bwihuse bushobora gukoreshwa, iterambere rya nepropatique rirashobora guhagarikwa cyangwa guhinduka.

Mugupima hakiri kare ibikomere bikabije byimpyiko (AKI), kwibanda kwa NGAL mumaraso ninkari mubisanzwe byiyongera byihuse, kandi 2h nimwe igaragara cyane (inshuro icumi kugeza ku magana kurenza agaciro gakomeye).Ibipimo gakondo nka serumu creatinine na urease mubisanzwe byiyongera cyane nyuma ya 24-72h.Kubwibyo, NGAL irashobora gukoreshwa mugupima hakiri kare AKI.NGAL irashobora kandi kwerekana uburemere bwimvune yimikorere yimpyiko.Irashobora gukoreshwa nkimwe mubipimo byerekana ibimenyetso bya AKI.

α1-Microglobuline ibaho cyane hejuru ya selile ya selile y'amazi atandukanye na lymphocytes.α1-Microglobuline ibaho mumaraso muburyo bubiri, ni ukuvuga, ubuntu α1-Microglobulin na IgA bihuza α1-Microglobuline (α 1mg-1Ga).Mubihe bisanzwe, α 1mg-1Ga bingana na 40-70% bya α1-Microglobuline yose mumaraso, kandi igipimo kiri hagati ya α1-Microglobuline na α 1mg-1Ga cyatewe nurwego rwa immunoglobuline mumaraso.Ubuntu α1-Microglobuline mu maraso burashobora kunyura mu isi ya filtration ya glomerular yisanzuye, kandi 95% -99% irasubizwa kandi igahinduka mu tubari twa mpyiko zegeranye, kandi umubare muto niwo usohoka mu nkari zanyuma.

Poroteyine ya Retinol ihuza vitamine mu maraso, igahuzwa n'umwijima kandi ikwirakwizwa cyane mu maraso, mu bwonko bwa cerebrospinal, inkari n'andi mazi yo mu mubiri.Kugena poroteyine ya retinol ihuza bishobora kwangiza imikorere yimpyiko hakiri kare kandi bikagaragaza urugero rwibyangiritse byimyanya ndangagitsina, bishobora gukoreshwa nkikimenyetso cyerekana imikorere yimpyiko hakiri kare no kuvura, ndetse no kwangiza imikorere yumwijima no gukurikirana imiti.

N.Uburemere bugereranije bwa NAG ni bunini kandi ntibushobora kuyungurura na glomerulus.Iyo impyiko yangiritse, irekurwa muri tubules yimpyiko ziva mu ngirabuzimafatizo, kandi inkari NAG ziyongera cyane.Igikorwa cy'inkari NAG ni kimwe mu bimenyetso byerekana kandi byihariye byerekana impyiko zifata impyiko, zishobora gukoreshwa nk'ikimenyetso cyo gusuzuma hakiri kare kwangirika kw'impyiko.