Lipid Metabolism Chemiluminescense Immunoassay Kit

Lipid metabolism bivuga igice kinini cyo gufata amavuta binyuze mumubiri wa emulisile mubice bito, pancreatic na mateste endocrine lipase hydrolysis ya acide yibinure mumavuta muri acide yubusa hamwe na monoester ya glycerol.Molekile ntoya ya hydrolyzed, nka glycerol, acide aciriritse na acide fatty acide, yinjizwa namara mato mumaraso.Nyuma yo kwinjiza monolipide hamwe na acide ndende ya fatty acide, triglyceride yabanje gusubizwa mu ngirabuzimafatizo ntoya yo mu mara hanyuma ikorwa na fosifolipide, cholesterol, na proteyine muri chylomicrons, inyura muri sisitemu ya lymphatique ikinjira mu maraso.

ApoA1 ni poroteyine nyamukuru yububiko bwa lipoproteine ​​(HDL) yuzuye, ishobora gukuramo cholesterol mu ngirabuzimafatizo no kwirinda aterosklerose.Kubwibyo, kugena ApoA1 bifatanije no kumenya ibindi bintu bya lipide (cholesterol, triglyceride, apolipoprotein B, nibindi) bifite agaciro ko kwisuzumisha mugupima indwara z'umutima.

ApoB ni poroteyine nyamukuru yubaka lipoprotein (LDL) nkeya, itwara cholesterol mu ngirabuzimafatizo bityo ikaba ifitanye isano no gukora plaque ya aterosklerotike.Kubwibyo, kugena ApoB bifatanije no kumenya ibindi bintu bya lipide (cholesterol, triglyceride, apolipoproteine ​​B, nibindi) bifite agaciro ko kwisuzumisha mugupima ibyago byindwara z'umutima zifata umutima hamwe na lipoprotein metabolism.

Lp (a) ni dimer igizwe na molekile ya LDL ihujwe na Apo (A), ifite ingaruka za aterogene.Lp (a) ni ibintu bishobora gutera indwara z'umutima zidashingiye ku bindi bipimo bya lipide, kandi bifite agaciro gakomeye ko guhanura indwara z'umutima, cyane cyane iyo Lp (A) na LDL byiyongereye icyarimwe.Kubwibyo, gutahura Lp (A) hamwe no kumenya ibindi bintu bya lipide bifite agaciro gakomeye nakamaro ko gusuzuma indwara zifasha no gusuzuma itandukaniro ryindwara zifata umutima, aterosklerose nizindi ndwara.

Triglyceride ni esters ikorwa nitsinda rya hydroxyl itatu muri glycerol na acide eshatu zumunyururu muremure.Igice cyakozwe mu mwijima ikindi gice kiva mu biryo byangiritse.Kugena triglyceride bikoreshwa mugupima no kugenzura neza diyabete, nepropatique, guhagarika umwijima, indwara ya lipide metabolism n'indwara zitandukanye za endocrine.Ifite akamaro kanini nagaciro mugusuzuma ubufasha no gusuzuma itandukaniro ryindwara yumutima hamwe na lipoproteinemia yumuryango.

Sintezike ya Cholesterol igaragara hose mu mubiri kandi ni igice kinini cyibice bigize selile na lipoproteine.Kugena cholesterol bifite akamaro kanini nagaciro mugusuzuma ibyago bya aterosklerose, kugenzura indwara ziterwa na lipide metabolism, kugenzura ingaruka zo kuvura, gusuzuma indwara zifasha no gusuzuma itandukaniro ryimirire mibi, indwara zumwijima nizindi ndwara ziterwa na metabolike.

Lipoproteine ​​yuzuye (HDL) ishinzwe gutwara cholesterol iva mu ngirabuzimafatizo zinjira mu mwijima.Mu mwijima, cholesterol ihinduka aside aside, inyura mu nzira ya biliary igana mu mara.Ubushakashatsi bw’ibyorezo n’ubuvuzi bwerekanye ko HDL-C ifitanye isano n’indwara zifata umutima, bityo rero ni ngombwa cyane gukurikirana ubushakashatsi bwa serumu HDL-C.Hejuru ya HDL-C ifasha kurinda indwara zifata umutima, mugihe HDL-C igabanutse cyane cyane iyo ijyanye no kwiyongera kwa triglyceride, byongera ibyago byindwara zifata umutima.Cholesterol ikomatanyirizwa hamwe na selile somatike kandi igakurwa mubiryo, itwarwa na lipoproteine ​​muri serumu.

Lipoprotein nkeya (LDL) igira uruhare mu gutwara cholesterol mu ngirabuzimafatizo, kandi LDL-C igira uruhare runini mu iterambere no gutera imbere kwa aterosklerose na coronari atherosclerose.Kubwibyo, gutahura LDL-C hamwe no kumenya ibindi bintu bya lipide bifite agaciro gakomeye nakamaro ko gusuzuma indwara zifasha no gusuzuma itandukaniro ryindwara zifata umutima, aterosklerose nizindi ndwara.