Immunoglobulin Chemiluminescense Immunoassay Kit

Indwara ya hepatite ya Autoimmune (AIH) n'indwara y'umwijima idakira, irangwa no kuzamuka kwa aminotransferase, kuba antibody irwanya nucleaire cyangwa antibody irwanya imitsi, hejuru ya immunoglobuline G (IgG), hamwe na hepatite / plasma-lymphocytic inflammation ishingiye ku mateka .Ubushakashatsi bwakozwe na epidemiologiya buherutse kwerekana ko ubwiyongere bwa AIH ku isi hose, cyane cyane ku barwayi b'abagabo;iyi myumvire irashobora kwerekana ihinduka ryibidukikije bitera indwara gutangira igihe.Kubera ko nta ndwara yihariye ya biomarker cyangwa ubushakashatsi bw’amateka iboneka muri iki gihe, AIH isaba kwisuzumisha kwa muganga, kandi hashyizweho uburyo bwo gutanga amanota yemewe bwo kwisuzumisha bufite umwihariko kandi bworoshye.Kubijyanye no kuvura, corticosteroide na azathioprine birasabwa, kandi mubagaragaza igisubizo kituzuye cyangwa abatihanganira iyi miti, havurwa umurongo wa kabiri, nka mycophenolate mofetil.Muri rusange, ibisubizo by'igihe kirekire ni byiza cyane ku barwayi bafite ibisubizo byuzuye bya biohimiki, mu gihe hashobora gukenerwa kuvurwa igihe kirekire kubera ko imiti ikingira indwara itera indwara.Acite-onset AIH ibaho, kandi kwisuzumisha biragoye cyane kubera kubura serumu autoantibodies cyangwa IgG yazamuye.Ibikenewe bidakenewe harimo kwisuzumisha hakiri kare, kwifashisha amabwiriza y’ubuvuzi yakwirakwijwe, no kumenyekanisha no kuzamura imibereho y’abarwayi ubuzima bwabo hamwe no gushyiraho uburyo bushya bwo kuvura corticosteroid.Immunoglobulin G nibintu byinshi birinda immunoglobuline muri serumu, bingana na 75-80% byamafaranga yose.Mu bantu bafite ubuzima bwiza, IgG irashobora kugabanywamo amoko ane: IgG1-IgG4, aho IgG4 idakunze kugaragara kandi ifite 1-7% gusa.Kuba hafi ya antigen igenewe ntibishobora gukora byuzuzanya, ariko birashobora kubuza ishingwa ryimikorere yubudahangarwa bwubundi bwoko.