Ibikoresho byo Kwambara Plasma Reagent Ikizamini
| Igisubizo cya Coagulation | ||
| Urukurikirane | izina RY'IGICURUZWA | Abbr |
| Imyambarire ya Plasma Reagent | Ikintu cyo Kwambara II-Kubura Plasma | F II |
| Kwambara Ibintu V-Kubura Plasma | FV | |
| Ikintu cyo Kwambara VII -Plasma Yuzuye | F VII | |
| Kwambara Ibintu X-Kubura Plasma | FX | |
| Ikintu cyo Kwambara VIII -Plasma Yuzuye | F VIII | |
| Ikintu cyo Kwambika IX-Kubura Plasma | F IX | |
| Kwambara Ibintu XI-Kubura Plasma | F XI | |
| Ikintu cyo Kwambara XII-Kubura Plasma | F XII | |
| Berichrom FXIII | F XIII | |
Ibintu byinshi byambaye imyenda yabanje kuvumburwa nkibikoresho bikora neza muri plasmas yabarwayi badasanzwe bafite ikibazo cyo kuragwa.Mu myaka ya za 1940 kugeza 1960, ibintu byinshi byiswe abashakashatsi batandukanye nyuma yizina ryumurwayi udafite ikintu gishya.Hariho ibintu bitandukanye byo kwifata biboneka mumaraso, bitwara kaskade yuzuye kandi kuva amaraso menshi birashobora gutera kubura kwifata.
Ibintu bya coagulation byagenwe numubare wabaroma kuburyo bukurikira: Factor XII, Factor XI, Factor IX, Factor VIII, Factor X, Factor V and Factor II Factor VII na FXIII.Impamvu zifatika zifatika zagenwe hamwe ninyongera “a,” urugero, FVIIIa, FIXa.Ibintu byo kwanduza byose bikorerwa muri hepatocytes yumwijima.
Kumenya ibintu bya coagulation birashobora kugerwaho hifashishijwe plasma fibrinogen (FIB) kugena ibirimo, plasma yibintu VIII, IX, XI na XII yibikorwa bya porokagulant, plasma yibintu II, V, VII na X igenzura ryibikorwa, plasma yibintu XIII Ikizamini cyujuje ubuziranenge na Plasma Factor XIII Subunit Antigen Kumenya.
Indwara ya coagulation factor deficiency disorders.Birangwa nibimenyetso bikunze kuva amaraso kuva mu bwana, hamwe namateka yumuryango. Uretse na hémofilia A na B, aribwo buryo bwo guhuza ibitsina chromosomal umurage, muri rusange ni umurage wa autosomal.Abagabo n'abagore barashobora kugira ingaruka, kandi akenshi hariho amateka yo gushyingiranwa.Indwara ziri muri iri tsinda zose ni ikintu kimwe cyo kubura coagulation, muri byo kubura VIII (hemophilia A) ni byo bikunze kugaragara, kandi izindi mpamvu zose usibye III na IV zirashobora kubura.
Indwara yo kubura ibintu.Byose ni kubura ibintu byinshi kandi bifite indwara zibanze.Ibisanzwe nko kubura vitamine K ni ibintu bya II, VII, IX, na X, ndetse n'indwara zikomeye z'umwijima. Gusuzuma ni ugusuzuma uburyo bwa coagulation no gukosora ibizamini.Kuvura plasma nshya cyangwa cryoprecipitate ni ingirakamaro, kandi kubarwayi babonye, indwara yibanze igomba kuvurwa
Ubushakashatsi bwinshi buvuga ko ibikorwa bya coagulation factor II ari ibisanzwe cyangwa byagabanutseho gato ku barwayi bafite hepatite ikaze na hepatite yoroheje idakira;ku barwayi bafite hepatite idakira, ikabije na cirrhose, urwego rwibikorwa bya coagulation factor II rwaragabanutse cyane, byerekana ko urugero rwo kugabanuka rufitanye isano na selile yumwijima.
Igikorwa cya coagulation factor V kigabanuka gusa mugihe imikorere yumwijima yangiritse cyangwa indwara yumwijima ikabije, kubwibyo bifatwa nkikimenyetso cyiza cyo gusuzuma imenyekanisha ry’abarwayi bafite umwijima.
Coagulation factor VII ifite igice gito cyubuzima (4 ~ 6h), kandi plasma iri hasi (0.5 ~ 2mg / L), bityo irashobora gukoreshwa nkikimenyetso cyo kwisuzumisha hakiri kare cyerekana imikorere ya protein ikora nabi kubarwayi barwaye umwijima.
